GlucoseScan

New-generation noninvasive glucose monitor
Problem
Every 11th person in the world suffers from diabetes. According to medical forecasts the number of patients will grow up to 40% by next 20 years. In order to avoid disease complication and carry well-being at desirable level patient has to constantly (3-7 times a day) measure blood glucose level. Traditional invasion methods are painful and expensive. Firstly, skin nyxises for daily blood tests fail to heal and could give quite unpleasant feelings. Secondly, test strips for blood glucose meter may cost up to 30-40k rubles (500-800 USD) a year.


Problem
Every 11th person in the world suffers from diabetes. According to medical forecasts the number of patients will grow up to 40% by next 20 years. In order to avoid disease complication and carry well-being at desirable level patient has to constantly (3-7 times a day) measure blood glucose level. Traditional invasion methods are painful and expensive. Firstly, skin nyxises for daily blood tests fail to heal and could give quite unpleasant feelings. Secondly, test strips for blood glucose meter may cost up to 30-40k rubles (500-800 USD) a year.
Goal
To develop device for blood sugar monitoring without blood sampling procedures and expensive consumables.
Requirements
  • Noninvasive method of blood sugar monitoring
  • High accuracy of results
  • No expensive consumables
  • Portability and independence
Solution
Development of device, that allows to monitor blood glucose level with ease and convenience with no nyxises required, based on spectral analysis theory. This device combines painless analysis method, high accuracy, portability that ensures independence and absence of expensive consumables

Noninvasive analysis method
Spectroscopy of combined diffusion is an optical non-destructive method of analysis based on light diffusion interacted with molecules.

Device transilluminates patient’s skin for 100 msecs, scattered light is observed at a scattering angle of 0 to 90 degrees, small spectrum corresponding to the combined scattering of sugars, then received value gets processed mathematically, and device displays blood glucose concentration level.



Precise analysis results
The most common issue with existing approaches to non-invasive analysis is the extremely low measurement accuracy, that makes it unsuitable for clinical use. Development of GlucoseScan solved this issue by using the most accurate optical method, based on analysis of the Raman scattering spectrum of human biological material. This method allowed to receive precise measurements with 8% of inaccuracy according to preliminary clinical approbation.
Cost efficiency
GlucoseScan is fully self-reliant and does not require additional consumables, that allows to reduce patient’s expenses.
Portability
Ergonomic design and autonomous work. GlucoseScan battery operated, up to 48 hours of autonomous work lets patient to have operating device by hand anywhere. This is quite important as patient has to conduct analysis 3−7 times per day.
Mobile app integration
Device can be controlled via application installed on smartphone or tablet. Moreover, GlucoseScan has display as well located on the device directly. Wireless connection to smartphone or tablet via built-in BLE module.

Summary
Team has completed an R&D stage and proved the Spectroscopy theory of combined diffusion in practice. Functional prototype, that able to measure blood glucose concentration level and display received data, was developed. R&D Team has also developed mobile application to control the device.
  • Noninvasive method of blood glucose level monitoring
  • Fully functional prototype of portable device
  • Product design of the device
  • Mobile application
DI Labs departments participated in development:
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